What is interesting here is that the mechanism of Ageing is more like a program triggering the catabolism of the body rather than a general deterioration. It turns out that the protein Sirt6 regulates telomerase production which determines the lenght of the telomeres. The protein also inhibits the production of another protein called NF Beta Kappa B which actively breaks body tissue down. SIRT6 is a cousin of SIRT1 which is also known to have anti-aging effects. SIRT1 is found naturally in Resveratrol in Grapes and Knot weed.

By Richard Alleyne

Researchers have found two connected chemical triggers that regulate the lifespan of cells and believe that, by influencing them, they can increase longevity and reduce the signs of ageing.
The study by Stanford University in California builds on the growing belief that age-related degeneration of tissues, organs and even facial skin, is an active, deliberate process by the body rather than a gradual failure of tired cells.
The team has found two proteins that seem to directly affect ageing. One – known as SIRT6 – which protects against cell ageing and another – known as NF Kappa B – which promotes it.
What is even more exciting is that the study has discovered for the first time that the two substances influence each other – and that manipulating their relative availability in the body could add years to the average life and reduce wrinkles…..
The scientists concluded that SIRT6 and NF Kappa B may work together to help cells age appropriately as the former “puts the brakes” on the latter. “It seems that an important job of SIRT6 is to restrain NF Kappa B and limit the expression of genes associated with ageing,” said Dr Chang.
Cont’ @ Source